The depot at Andersonville is not original to the town, having been moved here in July 1974 from the Taylor County community of Mauk. Andersonville uses the building as a welcome center and museum.
Built in the early 1900s for the Atlanta, Birmingham & Atlantic Railroad, it is similar to AB&A depots in Tifton and Ideal, as well as Montezuma's AB&A depot, which was moved to the Georgia Museum of Agriculture at Tifton.
In the 1970s the tiny village of Andersonville sought to gain some tourist traffic from the thousands who visited the nearby national cemetery and prison site. Several commercial structures were given facelifts and new paint, and an unsightly metal building was removed. It was thought that a train station would serve as an appropriate visitors center, but the town's own Central of Georgia depot had been demolished. The picturesque depot at Mauk was discovered to be available, so it was moved 60 miles to Andersonville.